MTND2P16

Across TCGA pan-cancer cohorts, MTND2P16 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MTND2P16 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTND2P16 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND2P16 expression acts as an unfavorable survival marker, although some lineages such as ACC and KICH show a favorable association.

UCS, TGCT, and DLBC are the cancer types where MTND2P16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	All	0.236	0.607	<.001	96	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
DLBC	OS	Tertile	All	0.591	0.948	<.001	69	view →
UCEC	DFS	Tertile	All	0.825	0.907	<.001	60	view →
HNSC	OS	Tertile	IV	0.442	0.624	.013	39	view →
GBM	OS	Tertile	All	0.201	0.439	.001	36	view →
ACC	DFS	Tertile	All	0.790	0.395	.006	24	view →
LIHC	OS	Tertile	All	0.558	0.727	.014	21	view →
KIRC	DFS	Tertile	IV	0.453	0.665	.012	19	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	12	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
KICH	DFS	Tertile	II,III,IV	0.931	0.561	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MTND2P16–UCS (DFS)

Open the UCS breakdown →