MTND1P28

Across TCGA pan-cancer cohorts, MTND1P28 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MTND1P28 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTND1P28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND1P28 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

UVM, ACC, and STAD are the cancer types where MTND1P28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	45	view →
STAD	OS	Quartile	II,III,IV	0.536	0.696	.002	35	view →
PCPG	OS	Tertile	All	0.505	0.945	.004	18	view →
KIRP	OS	Tertile	III,IV	0.268	0.808	.012	18	view →
THYM	OS	Tertile	II,III,IV	0.778	0.982	.036	9	view →
ESCA	DFS	Quartile	III,IV	0.531	0.254	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MTND1P28–UVM (DFS)

Open the UVM breakdown →