Q-omics provides the consensus-scored MTND1P27 profile across patient tissues and cancer cell-line models. MTND1P27 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, MTND1P27 is differentially expressed in 3, with the highest sampling consensus in HNSC. Additionally, MTND1P27 RNA expression shows 4,777 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight UCS, HNSC, and LAML as cancer lineages where MTND1P27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND1P27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND1P27 survival associations across molecular data types. MTND1P27 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND1P27 RNA expression–survival associations across cancer types. High MTND1P27 expression shows unfavorable associations in UCS, LUAD, LIHC, MESO, DLBC and ESCA. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for MTND1P27 RNA expression.
This table summarizes MTND1P27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MTND1P27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND1P27 shows lower tumor expression in HNSC and KIRC and higher tumor expression in THCA. The HNSC box plot shows higher MTND1P27 RNA expression in normal versus tumor tissue (log2 FC = −0.008, t-test p = .042).
This table shows molecular features associated with MTND1P27 in patient tissues and cancer cell lines. In patient samples, MTND1P27 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
