MTND1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MTND1P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MTND1P2 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher MTND1P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND1P2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUSC show a favorable association.

DLBC, COAD, and BLCA are the cancer types where MTND1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCDFSTertileAll0.3380.795.01049view →
COADOSTertileIV0.2270.690<.00136view →
BLCADFSTertileAll0.7990.303.03218view →
LGGOSTertileAll0.6300.868<.00118view →
LUSCOSTertileII,III,IV0.6750.356.01612view →
SARCDFSTertileAll0.1680.508<.0019view →
ACCOSTertileIII,IV0.1890.764.0049view →
SKCMDFSTertileIV0.0360.433<.0019view →
THYMOSTertileAll0.5720.934.0126view →
THCAOSTertileIV0.5890.887.0346view →
PCPGDFSTertileAll0.7340.922.0236view →
STADDFSMedianIII,IV0.4860.696.0273view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MTND1P2–DLBC (DFS)

Kaplan–Meier survival curve for MTND1P2 RNA-high vs -low samples in DLBC.

Open the DLBC breakdown →

Exploration