Across TCGA pan-cancer cohorts, MTND1P18 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTND1P18’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MTND1P18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND1P18 is over-expressed in tumor.
BRCA are the cancer types where MTND1P18 tumor–normal differential expression is most reproducible.