MTMR9

Across TCGA patient cohorts, MTMR9 mutation is significantly associated with the RNA expression of many other genes, with 3,587 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTMR9-associated genes across cancer lineages are MT-TW, RNU4-65P, and RPL38P3. Each is linked with MTMR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR9-to-partner and partner-to-MTMR9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT-TW grouped by MTMR9-low versus MTMR9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR9→partner) and Y-score (partner→MTMR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MT-TW →	+1.281	+4.215	<.001	.009	3	2
SKCM	RNU4-65P →	+0.281	+5.328	<.001	.003	3	2
COAD	RPL38P3 →	+0.794	+3.082	<.001	.007	3	2
CESC	MIR5699 →	+0.393	+5.201	<.001	.007	3	2
CESC	RN7SL66P →	+0.144	+5.010	<.001	.009	3	2
LUAD	RNA5SP482 →	+0.258	+5.748	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,587 associations by consensus.

MT-TW by MTMR9 expression — SKCM

Explore this box plot interactively →