MTMR9

Across TCGA cell cohorts, MTMR9 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTMR9-associated genes across cancer lineages are F9, WFDC12, and DIRC1. Each is linked with MTMR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR9-to-partner and partner-to-MTMR9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F9 grouped by MTMR9-low versus MTMR9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR9→partner) and Y-score (partner→MTMR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	F9 →	+0.014	+4.969	<.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.249	+4.874	<.001	.002	3	1
BLOOD_Leukemia	DIRC1 →	+0.037	+4.969	<.001	.003	3	1
BLOOD_Leukemia	CYP4A11 →	+0.050	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR5H6 →	+0.427	+4.705	<.001	.003	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

F9 by MTMR9 expression — BLOOD_Leukemia

Explore this box plot interactively →