MTMR6

Across TCGA pan-cancer cohorts, MTMR6 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MTMR6 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MTMR6 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MTMR6 expression acts as an unfavorable survival marker.

LSCC, PDAC, and LUAD are the cancer types where MTMR6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.663	0.894	.007	18	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	15	view →
LUAD	OS	Tertile	III,IV	0.426	1.000	.012	8	view →
HNSC	DFS	Median	II,III,IV	0.902	0.967	.027	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MTMR6–LSCC (OS)

Open the LSCC breakdown →