MTMR6

Across TCGA cell cohorts, MTMR6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,996 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTMR6-associated GO terms across cancer lineages are Nucleotide-excision repair, DNA gap filling, Phosphatidylinositol dephosphorylation, and Regulation of chromosome segregation. Each is linked with MTMR6 in more than 12 cancer types. Because this analysis shows association rather than direction, both MTMR6-to-partner and partner-to-MTMR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair, DNA gap filling grouped by MTMR6-low versus MTMR6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR6→partner) and Y-score (partner→MTMR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nucleotide-excision repair, DNA gap filling →	+0.104	+0.931	<.001	<.001	3	13
LIVER	Phosphatidylinositol dephosphorylation →	+0.081	+0.755	<.001	<.001	3	13
CNS	Regulation of chromosome segregation →	+0.055	+0.590	.008	.001	3	12
SKIN	Regulation of endoplasmic reticulum tubular network organization →	+0.095	+0.732	<.001	<.001	3	12
BLOOD_Myeloma	Negative regulation of hematopoietic stem cell differentiation →	+0.187	+1.172	<.001	.001	3	10
BLOOD_Leukemia	Retrograde transport, vesicle recycling within Golgi →	+0.101	+0.963	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,996 associations by consensus.

Nucleotide-excision repair, DNA gap filling by MTMR6 expression — SKIN

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