MTMR4

Across TCGA patient cohorts, MTMR4 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,944 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTMR4-associated proteins across cancer lineages are EIF2AK3, HECTD1_S1487, and MTMR4_S629. Each is linked with MTMR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR4-to-partner and partner-to-MTMR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTMR4 versus EIF2AK3 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR4→partner) and Y-score (partner→MTMR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EIF2AK3 →	+0.469	+0.468	<.001	<.001	3	2
LUAD	HECTD1_S1487 →	-0.695	-0.281	<.001	<.001	3	2
BRCA	MTMR4_S629 →	+0.980	+0.679	<.001	<.001	3	2
BRCA	NCOR1_T590 →	-0.807	-0.816	.002	.002	3	2
BRCA	BIRC6_S2222 →	+0.983	+0.593	.001	.004	3	1
BRCA	CBX8_S332 →	+0.975	+0.760	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,944 associations by consensus.

MTMR4 vs EIF2AK3 — LSCC

Explore this scatter interactively →