MTMR2

Across TCGA patient cohorts, MTMR2 protein abundance is significantly associated with the RNA expression of many other genes, with 20,130 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTMR2-associated genes across cancer lineages are CASC15, UCHL1, and ACTA2. Each is linked with MTMR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTMR2-to-partner and partner-to-MTMR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTMR2 versus CASC15 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR2→partner) and Y-score (partner→MTMR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CASC15 →	+0.773	+0.211	<.001	<.001	3	6
LSCC	UCHL1 →	+1.698	+0.219	<.001	<.001	3	6
UCEC	ACTA2 →	+1.567	+0.230	<.001	<.001	3	5
BRCA	AKT3 →	+0.845	+0.250	<.001	<.001	3	5
LSCC	SGIP1 →	+0.757	+0.227	<.001	.001	3	5
UCEC	CNN1 →	+1.676	+0.220	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,130 associations by consensus.

MTMR2 vs CASC15 — LSCC

Explore this scatter interactively →