MTMR14

Across TCGA cell cohorts, MTMR14 mutation is significantly associated with the RNA expression of many other genes, with 110 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTMR14-associated genes across cancer lineages are RNF167, CRACD, and ZBTB45. Each is linked with MTMR14 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR14-to-partner and partner-to-MTMR14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF167 grouped by MTMR14-low versus MTMR14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR14→partner) and Y-score (partner→MTMR14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNF167 →	+0.494	+3.212	.002	.006	3	1
LARGE_INTESTINE	CRACD →	+1.022	+3.212	.004	.006	3	1
LARGE_INTESTINE	ZBTB45 →	+0.844	+3.212	.001	.006	3	1
LARGE_INTESTINE	RDH10 →	+0.812	+3.212	.006	.006	3	1
LARGE_INTESTINE	GPR108 →	+0.594	+3.212	<.001	.006	3	1
LARGE_INTESTINE	GALR3 →	+0.091	+3.865	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

RNF167 by MTMR14 expression — LARGE_INTESTINE

Explore this box plot interactively →