MTMR11

Across TCGA cell cohorts, MTMR11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,799 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MTMR11-associated GO terms across cancer lineages are Actin filament depolymerization, Fibroblast migration, and Regulation of cardiac muscle adaptation. Each is linked with MTMR11 in more than 10 cancer types. Because this analysis shows association rather than direction, both MTMR11-to-partner and partner-to-MTMR11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by MTMR11-low versus MTMR11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR11→partner) and Y-score (partner→MTMR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament depolymerization →	+0.156	+1.537	.004	.001	3	11
STOMACH	Fibroblast migration →	+0.264	+2.177	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of cardiac muscle adaptation →	+0.324	+1.364	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of cardiac muscle hypertrophy in response to stress →	+0.324	+1.364	<.001	<.001	3	10
BONE	Regulation of cell-matrix adhesion →	+0.116	+1.443	<.001	<.001	3	10
STOMACH	Actin filament capping →	+0.182	+2.143	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,799 associations by consensus.

Actin filament depolymerization by MTMR11 expression — BONE

Explore this box plot interactively →