MTMR10

Across TCGA pan-cancer cohorts, MTMR10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MTMR10 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MTMR10 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MTMR10 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and OV are the cancer types where MTMR10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.708	0.368	<.001	35	view →
UCEC	OS	Tertile	All	1.000	0.823	.009	12	view →
OV	DFS	Tertile	All	1.000	0.645	.047	8	view →
GBM	OS	Median	All	0.940	0.777	.008	5	view →
CCRCC	OS	Median	All	0.983	0.903	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MTMR10–PDAC (OS)

Open the PDAC breakdown →