MTMR1

Across TCGA patient cohorts, MTMR1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTMR1-associated genes across cancer lineages are ADAMTS4, PLVAP, and SAMD12. Each is linked with MTMR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MTMR1-to-partner and partner-to-MTMR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTMR1 versus ADAMTS4 in CCRCC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR1→partner) and Y-score (partner→MTMR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADAMTS4 →	-1.014	-0.120	<.001	.001	3	4
CCRCC	PLVAP →	-1.035	-0.116	<.001	<.001	3	4
HNSC	SAMD12 →	+1.401	+0.197	<.001	.003	3	4
HNSC	SRGAP3 →	+0.772	+0.217	<.001	<.001	3	4
CCRCC	SIRPB3P →	+0.624	+0.157	<.001	<.001	3	4
GBM	SYNGR1 →	+1.048	+0.269	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,550 associations by consensus.

MTMR1 vs ADAMTS4 — CCRCC

Explore this scatter interactively →