MTMR1

Across TCGA cell cohorts, MTMR1 protein abundance is significantly associated with the go_rna of many other GO terms, with 3,003 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTMR1-associated GO terms across cancer lineages are Establishment of sister chromatid cohesion, Rostrocaudal neural tube patterning, and Regulation of systemic arterial blood pressure mediated by a chemical signal. Each is linked with MTMR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MTMR1-to-partner and partner-to-MTMR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of sister chromatid cohesion grouped by MTMR1-low versus MTMR1-high in UPPER_AERODIGESTIVE_TRACT.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR1→partner) and Y-score (partner→MTMR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of sister chromatid cohesion →	+0.125	+0.262	.007	.009	3	7
OVARY	Rostrocaudal neural tube patterning →	+0.182	+0.406	.001	<.001	3	6
OVARY	Regulation of systemic arterial blood pressure mediated by a chemical signal →	-0.288	-0.519	<.001	<.001	3	6
LUNG_SCLC	Constitutive heterochromatin formation →	+0.092	+0.387	<.001	<.001	3	6
OVARY	Maintenance of sister chromatid cohesion →	+0.093	+0.563	.006	<.001	3	6
OVARY	Maintenance of mitotic sister chromatid cohesion →	+0.093	+0.563	.006	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,003 associations by consensus.

Establishment of sister chromatid cohesion by MTMR1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →