MTM1

Across TCGA cell cohorts, MTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,316 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MTM1-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Phosphatidylinositol metabolic process, and Negative regulation of autophagosome assembly. Each is linked with MTM1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MTM1-to-partner and partner-to-MTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by MTM1-low versus MTM1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTM1→partner) and Y-score (partner→MTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Phosphatidylinositol biosynthetic process →	+0.071	+0.989	<.001	.003	3	17
LUNG_NSCLC_LUSC	Phosphatidylinositol metabolic process →	+0.058	+0.957	.006	.001	2	15
BONE	Negative regulation of autophagosome assembly →	+0.151	+0.649	.008	.004	2	15
BONE	Phospholipid dephosphorylation →	+0.058	+0.738	<.001	.003	2	15
BONE	Phosphatidylinositol dephosphorylation →	+0.074	+0.759	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of vacuole organization →	+0.073	+0.974	.003	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,316 associations by consensus.

Phosphatidylinositol biosynthetic process by MTM1 expression — BONE

Explore this box plot interactively →