Across TCGA pan-cancer cohorts, MTIF2P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTIF2P1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where MTIF2P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTIF2P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
LUAD, LUSC, and STAD are the cancer types where MTIF2P1 tumor–normal differential expression is most reproducible.