MTIF2

Across TCGA patient cohorts, MTIF2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,547 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTIF2-associated genes across cancer lineages are CNRIP1, PMP22, and COLEC12. Each is linked with MTIF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MTIF2-to-partner and partner-to-MTIF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTIF2 versus CNRIP1 in OV, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTIF2→partner) and Y-score (partner→MTIF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CNRIP1 →	-0.830	-0.321	<.001	.003	3	8
OV	PMP22 →	-1.005	-0.354	<.001	<.001	3	7
BRCA	COLEC12 →	-1.091	-0.210	<.001	.001	3	7
OV	CAVIN1 →	-1.187	-0.380	<.001	<.001	3	7
OV	MRC1 →	-1.140	-0.360	<.001	<.001	3	7
OV	LOX →	-1.520	-0.317	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,547 associations by consensus.

MTIF2 vs CNRIP1 — OV

Explore this scatter interactively →