MTHFSD

Across TCGA patient cohorts, MTHFSD RNA expression is significantly associated with the protein abundance of many other proteins, with 12,061 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTHFSD-associated proteins across cancer lineages are CFDP1, DHX38, and MVD. Each is linked with MTHFSD in more than 7 cancer types. Because this analysis shows association rather than direction, both MTHFSD-to-partner and partner-to-MTHFSD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTHFSD versus CFDP1 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFSD→partner) and Y-score (partner→MTHFSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CFDP1 →	+0.366	+0.373	<.001	<.001	3	8
HNSC	DHX38 →	+0.282	+0.444	<.001	<.001	3	6
BRCA	MVD →	+0.476	+0.342	<.001	.001	3	5
HNSC	ZC3H18 →	+0.290	+0.549	<.001	<.001	3	5
GBM	GTF2I →	+0.389	+0.260	<.001	<.001	3	5
BRCA	CSNK2A2 →	+0.197	+0.336	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,061 associations by consensus.

MTHFSD vs CFDP1 — GBM

Explore this scatter interactively →