MTHFS

Across TCGA patient cohorts, MTHFS mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTHFS-associated genes across cancer lineages are Neutrophils. Each is linked with MTHFS in more than 1 cancer types. Because this analysis shows association rather than direction, both MTHFS-to-partner and partner-to-MTHFS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by MTHFS-low versus MTHFS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFS→partner) and Y-score (partner→MTHFS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Neutrophils →	+0.040	+2.751	<.001	.044	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Neutrophils by MTHFS expression — UCEC

Explore this box plot interactively →