MTHFD2P7

Across TCGA patient cohorts, MTHFD2P7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,759 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P7-associated GO terms across cancer lineages are Regulation of translational initiation in response to stress, Response to ionizing radiation, and Vesicle cargo loading. Each is linked with MTHFD2P7 in more than 19 cancer types. Because this analysis shows association rather than direction, both MTHFD2P7-to-partner and partner-to-MTHFD2P7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation in response to stress grouped by MTHFD2P7-low versus MTHFD2P7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P7→partner) and Y-score (partner→MTHFD2P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of translational initiation in response to stress →	+0.067	+0.195	<.001	<.001	3	20
ESCA	Response to ionizing radiation →	+0.037	+0.167	.003	<.001	3	19
STAD	Vesicle cargo loading →	+0.060	+0.167	<.001	<.001	3	19
STAD	Regulation of translation in response to endoplasmic reticulum stress →	+0.067	+0.229	<.001	<.001	3	19
ESCA	Negative regulation of DNA replication →	+0.067	+0.262	.001	<.001	3	19
ESCA	Cellular response to radiation →	+0.061	+0.217	.004	.003	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,759 associations by consensus.

Regulation of translational initiation in response to stress by MTHFD2P7 expression — STAD

Explore this box plot interactively →