Across TCGA patient cohorts, MTHFD2P5 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,338 significant associations in total. OV shows the largest number of these associations.

The most reproducible MTHFD2P5-associated proteins across cancer lineages are MPI, SPARCL1_S59, and MKI67_S2708. Each is linked with MTHFD2P5 in more than 2 cancer types. Because this analysis shows association rather than direction, both MTHFD2P5-to-partner and partner-to-MTHFD2P5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P5→partner) and Y-score (partner→MTHFD2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MPI →	-0.268	-0.300	.007	.002	3	3
BRCA	SPARCL1_S59 →	-0.930	-0.389	.006	.004	3	3
BRCA	MKI67_S2708 →	+0.772	+0.506	<.001	.001	3	2
LUAD	NT5C3A_S273 →	+0.583	+0.142	.001	.002	3	2
BRCA	SLF2_S701 →	+0.484	+0.464	<.001	<.001	3	2
OV	SURF6_S138 →	+0.729	+0.542	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,338 associations by consensus.

Exploration

MTHFD2P5 survival (RNA) · tumor vs normal (RNA) · all MTHFD2P5 data types