MTHFD2P5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTHFD2P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,135 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P5-associated GO terms across cancer lineages are Amino acid metabolic process, Meiotic cell cycle process, and Alpha-amino acid metabolic process. Each is linked with MTHFD2P5 in more than 10 cancer types. Because this analysis shows association rather than direction, both MTHFD2P5-to-partner and partner-to-MTHFD2P5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P5→partner) and Y-score (partner→MTHFD2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADAmino acid metabolic process →+0.026+0.062<.001<.001310
STADMeiotic cell cycle process →+0.031+0.065<.001<.00139
THYMAlpha-amino acid metabolic process →+0.032+0.010.003.004111
DLBCPositive regulation of mitotic cell cycle →+0.054+0.073<.001<.00139
STADResponse to gamma radiation →+0.029+0.053<.001<.00139
STADRegulation of DNA damage checkpoint →+0.045+0.061<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,135 associations by consensus.

Exploration