MTHFD2P4

Across TCGA patient cohorts, MTHFD2P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,274 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P4-associated GO terms across cancer lineages are Regulation of reproductive process, Regulation of hormone secretion, and Vesicle localization. Each is linked with MTHFD2P4 in more than 4 cancer types. Because this analysis shows association rather than direction, both MTHFD2P4-to-partner and partner-to-MTHFD2P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of reproductive process grouped by MTHFD2P4-low versus MTHFD2P4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P4→partner) and Y-score (partner→MTHFD2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of reproductive process →	+0.049	+0.036	<.001	<.001	3	5
STAD	Regulation of hormone secretion →	+0.051	+0.022	<.001	<.001	3	4
STAD	Vesicle localization →	+0.092	+0.042	<.001	<.001	3	4
STAD	Regulation of mitochondrion organization →	+0.103	+0.048	<.001	<.001	3	4
STAD	Telencephalon development →	+0.063	+0.047	<.001	<.001	3	4
STAD	Negative regulation of type I interferon production →	+0.071	+0.018	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,274 associations by consensus.

Regulation of reproductive process by MTHFD2P4 expression — STAD

Explore this box plot interactively →