MTHFD2P1

Across TCGA patient cohorts, MTHFD2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,930 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P1-associated GO terms across cancer lineages are Nucleoside phosphate biosynthetic process, Regulation of actin filament organization, and Positive regulation of proteolysis involved in protein catabolic process. Each is linked with MTHFD2P1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MTHFD2P1-to-partner and partner-to-MTHFD2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside phosphate biosynthetic process grouped by MTHFD2P1-low versus MTHFD2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P1→partner) and Y-score (partner→MTHFD2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside phosphate biosynthetic process →	+0.062	+0.141	<.001	<.001	3	15
STAD	Regulation of actin filament organization →	+0.074	+0.166	<.001	<.001	3	14
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.070	+0.173	<.001	<.001	3	14
STAD	Regulation of cysteine-type endopeptidase activity →	+0.063	+0.143	<.001	<.001	3	14
STAD	Stress-activated protein kinase signaling cascade →	+0.068	+0.141	<.001	<.001	3	14
STAD	Obsolete cellular response to extracellular stimulus →	+0.066	+0.150	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,930 associations by consensus.

Nucleoside phosphate biosynthetic process by MTHFD2P1 expression — STAD

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