MTHFD1P1

Across TCGA patient cohorts, MTHFD1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,766 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTHFD1P1-associated proteins across cancer lineages are DAB2_S394, MYEF2_S17, and PDS5A_T1208. Each is linked with MTHFD1P1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MTHFD1P1-to-partner and partner-to-MTHFD1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTHFD1P1 versus DAB2_S394 in GBM, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD1P1→partner) and Y-score (partner→MTHFD1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DAB2_S394 →	-0.394	-0.425	<.001	<.001	3	4
HNSC	MYEF2_S17 →	+0.797	+0.575	<.001	<.001	3	4
OV	PDS5A_T1208 →	+0.697	+0.359	.004	.006	2	5
BRCA	RILPL1 →	-0.361	-0.370	<.001	<.001	3	4
HNSC	RPRD2 →	+0.365	+0.857	<.001	<.001	3	4
GBM	CBX3 →	+0.417	+0.372	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,766 associations by consensus.

MTHFD1P1 vs DAB2_S394 — GBM

Explore this scatter interactively →