MTG2

Across TCGA cell cohorts, MTG2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTG2-associated genes across cancer lineages are MS4A7, TAFA1, and MINAR2. Each is linked with MTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTG2-to-partner and partner-to-MTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A7 grouped by MTG2-low versus MTG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTG2→partner) and Y-score (partner→MTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MS4A7 →	+0.030	+3.942	.006	.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.209	+2.688	.003	.008	3	1
LARGE_INTESTINE	MINAR2 →	+0.027	+2.882	.003	.005	3	1
LARGE_INTESTINE	KRTAP10-12 →	+0.051	+3.247	<.001	.001	3	1
LARGE_INTESTINE	DAZ2 →	+0.127	+3.678	.004	.001	3	1
LARGE_INTESTINE	KRTAP5-8 →	+0.079	+3.228	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

MS4A7 by MTG2 expression — LARGE_INTESTINE

Explore this box plot interactively →