MTFR2P2

Across TCGA pan-cancer cohorts, MTFR2P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MTFR2P2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTFR2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTFR2P2 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LGG show a favorable association.

UVM, DLBC, and LUSC are the cancer types where MTFR2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.136	0.919	<.001	90	view →
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	63	view →
LUSC	DFS	Tertile	All	0.816	0.697	.001	42	view →
LGG	OS	Median	All	0.880	0.742	.003	27	view →
READ	DFS	Tertile	III,IV	0.141	0.777	<.001	27	view →
CESC	DFS	Quartile	All	0.856	0.702	.007	24	view →
HNSC	DFS	Quartile	III,IV	0.314	0.556	.013	17	view →
SKCM	OS	Quartile	All	0.223	0.341	.011	11	view →
PAAD	DFS	Tertile	All	0.219	0.514	.045	9	view →
LIHC	OS	Tertile	III,IV	0.119	0.535	.035	9	view →
KIRC	DFS	Tertile	All	0.368	0.636	.031	6	view →
UCS	OS	Tertile	II,III,IV	0.865	0.522	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MTFR2P2–UVM (OS)

Open the UVM breakdown →