MTFR1L

Across TCGA patient cohorts, MTFR1L mutation is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTFR1L-associated genes across cancer lineages are RNU6-906P, UBE2V1P4, and LINC01519. Each is linked with MTFR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both MTFR1L-to-partner and partner-to-MTFR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-906P grouped by MTFR1L-low versus MTFR1L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTFR1L→partner) and Y-score (partner→MTFR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-906P →	+0.308	+3.792	<.001	.004	3	2
CESC	UBE2V1P4 →	+0.134	+5.103	<.001	.008	3	1
CESC	LINC01519 →	+0.024	+5.669	<.001	.003	3	1
CESC	PRAMEF11 →	+0.034	+5.969	<.001	.002	3	1
CESC	LINC02226 →	+0.040	+5.201	<.001	.007	3	1
CESC	SLC25A5P9 →	+0.069	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

RNU6-906P by MTFR1L expression — BLCA

Explore this box plot interactively →