MTFR1

Across TCGA cell cohorts, MTFR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,458 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTFR1-associated GO terms across cancer lineages are Blastocyst growth, Anterograde dendritic transport of messenger ribonucleoprotein complex, and Intracellular distribution of mitochondria. Each is linked with MTFR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MTFR1-to-partner and partner-to-MTFR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by MTFR1-low versus MTFR1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTFR1→partner) and Y-score (partner→MTFR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Blastocyst growth →	+0.126	+0.763	<.001	.001	3	11
PANCREAS	Anterograde dendritic transport of messenger ribonucleoprotein complex →	+0.161	+0.836	<.001	.004	3	10
CNS	Intracellular distribution of mitochondria →	+0.141	+0.679	.001	<.001	3	10
BLOOD_Lymphoma	Double-strand break repair via nonhomologous end joining →	+0.034	+0.810	.003	<.001	2	11
OVARY	Double-strand break repair via alternative nonhomologous end joining →	+0.106	+0.848	<.001	<.001	3	9
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.092	+0.683	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,458 associations by consensus.

Blastocyst growth by MTFR1 expression — BLOOD_Lymphoma

Explore this box plot interactively →