MTFP1

Across TCGA cell cohorts, MTFP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,534 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MTFP1-associated GO terms across cancer lineages are Nuclear DNA replication, DNA replication initiation, and DNA replication checkpoint signaling. Each is linked with MTFP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MTFP1-to-partner and partner-to-MTFP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear DNA replication grouped by MTFP1-low versus MTFP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTFP1→partner) and Y-score (partner→MTFP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear DNA replication →	+0.150	+1.186	<.001	<.001	3	13
BONE	DNA replication initiation →	+0.153	+1.211	<.001	<.001	3	13
BONE	DNA replication checkpoint signaling →	+0.163	+1.058	<.001	<.001	3	13
BREAST	Mitotic DNA replication checkpoint signaling →	+0.135	+1.279	<.001	<.001	3	12
SKIN	Meiotic chromosome separation →	+0.349	+1.136	.004	<.001	3	12
BONE	Cell cycle DNA replication →	+0.148	+1.186	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,534 associations by consensus.

Nuclear DNA replication by MTFP1 expression — BONE

Explore this box plot interactively →