Across TCGA patient cohorts, MTF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible MTF1-associated GO terms across cancer lineages are Endosomal transport, Obsolete selective autophagy, and Autophagosome maturation. Each is linked with MTF1 in more than 33 cancer types. Because this analysis shows association rather than direction, both MTF1-to-partner and partner-to-MTF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTF1→partner) and Y-score (partner→MTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Endosomal transport →	+0.062	+0.661	<.001	<.001	3	34
THYM	Obsolete selective autophagy →	+0.070	+0.876	<.001	<.001	3	34
SCLC	Autophagosome maturation →	+0.083	+0.583	<.001	<.001	3	33
THYM	Regulation of macroautophagy →	+0.067	+0.856	<.001	<.001	3	33
SCLC	Negative regulation of macroautophagy →	+0.076	+0.578	<.001	<.001	3	33
SCLC	Cytosolic transport →	+0.074	+0.755	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Exploration

MTF1 survival (RNA) · tumor vs normal (RNA) · all MTF1 data types