Across TCGA patient cohorts, MTF1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,661 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTF1-associated genes across cancer lineages are EBNA1BP2, NRSN2, and CAP1. Each is linked with MTF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MTF1-to-partner and partner-to-MTF1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTF1→partner) and Y-score (partner→MTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EBNA1BP2 →	+1.026	+0.488	.006	.004	3	3
HNSC	NRSN2 →	-0.954	-0.476	<.001	<.001	3	3
HNSC	CAP1 →	+0.666	+0.360	.001	<.001	3	3
LSCC	FREM2 →	-2.013	-0.358	<.001	<.001	3	3
HNSC	ZC3H12A →	+0.812	+0.402	.002	.002	3	3
HNSC	SF3A3 →	+0.571	+0.366	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,661 associations by consensus.

Exploration

MTF1 survival (RNA) · tumor vs normal (RNA) · all MTF1 data types