Across TCGA cell cohorts, MTF1 mutation is significantly associated with the RNA expression of many other genes, with 828 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTF1-associated genes across cancer lineages are OR2A2, OR2J2, and TCF23. Each is linked with MTF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTF1-to-partner and partner-to-MTF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTF1→partner) and Y-score (partner→MTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR2A2 →	+0.046	+5.087	<.001	.004	3	2
BLOOD_Lymphoma	OR2J2 →	+0.035	+5.247	<.001	.001	3	2
KIDNEY	TCF23 →	+0.006	+5.000	<.001	.005	3	1
KIDNEY	FAM216B →	+0.103	+5.000	<.001	.005	3	1
KIDNEY	KIR2DL3 →	+0.013	+5.000	<.001	.005	3	1
KIDNEY	TIFAB →	+0.013	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 828 associations by consensus.

Exploration

MTF1 survival (RNA) · tumor vs normal (RNA) · all MTF1 data types