MTERF4

Across TCGA cell cohorts, MTERF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,129 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTERF4-associated GO terms across cancer lineages are Chromosome separation, Otolith mineralization, and Transcription elongation-coupled chromatin remodeling. Each is linked with MTERF4 in more than 15 cancer types. Because this analysis shows association rather than direction, both MTERF4-to-partner and partner-to-MTERF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome separation grouped by MTERF4-low versus MTERF4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTERF4→partner) and Y-score (partner→MTERF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chromosome separation →	+0.158	+0.666	.001	.003	3	16
SKIN	Otolith mineralization →	+0.143	+0.581	<.001	<.001	3	15
SOFT_TISSUE	Transcription elongation-coupled chromatin remodeling →	+0.091	+0.724	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Constitutive heterochromatin formation →	+0.089	+0.866	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.069	+1.010	.001	<.001	3	13
SOFT_TISSUE	Heterochromatin organization →	+0.070	+0.741	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,129 associations by consensus.

Chromosome separation by MTERF4 expression — BONE

Explore this box plot interactively →