MTERF3

Across TCGA cell cohorts, MTERF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,717 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MTERF3-associated GO terms across cancer lineages are DNA replication, Protein localization to condensed chromosome, and Reciprocal homologous recombination. Each is linked with MTERF3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MTERF3-to-partner and partner-to-MTERF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by MTERF3-low versus MTERF3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTERF3→partner) and Y-score (partner→MTERF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.122	+1.031	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.135	+0.919	.001	<.001	3	16
BREAST	Reciprocal homologous recombination →	+0.067	+0.871	<.001	<.001	3	15
BLOOD_Myeloma	DNA-templated DNA replication →	+0.110	+1.145	<.001	.001	3	15
LARGE_INTESTINE	Blastocyst growth →	+0.201	+0.814	<.001	<.001	3	15
KIDNEY	Protein localization to kinetochore →	+0.150	+0.828	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,717 associations by consensus.

DNA replication by MTERF3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →