MTERF2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTERF2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,115 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MTERF2-associated genes across cancer lineages are FCGRT, PEX11G, and PDE10A. Each is linked with MTERF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTERF2-to-partner and partner-to-MTERF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTERF2 versus FCGRT in CCRCC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTERF2→partner) and Y-score (partner→MTERF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCFCGRT →+0.632+1.362.001.00531
CCRCCPEX11G →+1.024+0.968.001.00931
CCRCCPDE10A →-2.092-1.286.004.00131
CCRCCBSPRY →+1.914+1.089.004.00131
CCRCCAREL1 →+0.387+1.004.006.00431
CCRCCEPCAM →+2.035+1.001<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,115 associations by consensus.

MTERF2 vs FCGRT — CCRCC

Per-sample scatter of MTERF2 vs FCGRT in CCRCC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration