MTERF2

Across TCGA patient cohorts, MTERF2 mutation is significantly associated with the RNA expression of many other genes, with 2,014 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTERF2-associated genes across cancer lineages are MIR8059, RNU6-1151P, and MIR4267. Each is linked with MTERF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTERF2-to-partner and partner-to-MTERF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8059 grouped by MTERF2-low versus MTERF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTERF2→partner) and Y-score (partner→MTERF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8059 →	+0.287	+2.123	.004	.009	3	2
KIRP	RNU6-1151P →	+0.587	+5.770	<.001	.003	3	2
BLCA	MIR4267 →	+0.580	+4.859	<.001	.004	3	2
BRCA	CRYGA →	+0.061	+4.527	<.001	.007	3	2
BRCA	MIR6853 →	+0.183	+7.057	<.001	.009	3	1
BRCA	PRAMEF13 →	+0.032	+6.001	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

MIR8059 by MTERF2 expression — UCEC

Explore this box plot interactively →