MTERF1

Across TCGA pan-cancer cohorts, MTERF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MTERF1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MTERF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTERF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where MTERF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.323	0.893	.010	12	view →
LSCC	OS	Quartile	All	0.756	1.000	.007	5	view →
CCRCC	OS	Median	III,IV	0.948	0.742	.046	2	view →
GBM	DFS	Median	All	0.217	0.548	.048	2	view →
HNSC	DFS	Median	III,IV	0.845	0.476	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MTERF1–LUAD (DFS)

Open the LUAD breakdown →