MTERF1

Across TCGA cell cohorts, MTERF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,883 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MTERF1-associated GO terms across cancer lineages are Mitochondrial RNA metabolic process, Replication fork processing, and DNA-templated DNA replication maintenance of fidelity. Each is linked with MTERF1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MTERF1-to-partner and partner-to-MTERF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA metabolic process grouped by MTERF1-low versus MTERF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTERF1→partner) and Y-score (partner→MTERF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial RNA metabolic process →	+0.126	+1.207	<.001	<.001	3	14
SOFT_TISSUE	Replication fork processing →	+0.130	+1.138	<.001	<.001	3	10
SOFT_TISSUE	DNA-templated DNA replication maintenance of fidelity →	+0.131	+0.920	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of DNA repair →	+0.095	+0.774	<.001	<.001	3	10
SOFT_TISSUE	Double-strand break repair via homologous recombination →	+0.104	+1.154	<.001	<.001	3	10
KIDNEY	tRNA dihydrouridine synthesis →	+0.123	+0.714	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,883 associations by consensus.

Mitochondrial RNA metabolic process by MTERF1 expression — BONE

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