MTDHP1

Across TCGA pan-cancer cohorts, MTDHP1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MTDHP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTDHP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTDHP1 is over-expressed in tumor.

KIRC, BLCA, and HNSC are the cancer types where MTDHP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTDHP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.160	<.001	11	view →
BLCA	All	All	+0.540	<.001	8	view →
HNSC	All	All	+0.194	.004	7	view →
LUSC	All	All	+0.186	.002	4	view →
LIHC	All	All	+0.184	<.001	4	view →
STAD	Male	IV	+0.440	.039	3	view →
COAD	All	All	+0.146	.006	3	view →
CHOL	Male	All	+0.803	<.001	2	view →
UCEC	All	All	+0.275	.032	2	view →
READ	All	All	+0.228	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MTDHP1–KIRC

Open the KIRC breakdown →