Across TCGA pan-cancer cohorts, MTCYBP8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTCYBP8’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MTCYBP8 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCYBP8 is over-expressed in tumor, although a few such as BRCA and LIHC show the opposite, repressed pattern.
BRCA and LIHC are the cancer types where MTCYBP8 tumor–normal differential expression is most reproducible.