MTCYBP28

Across TCGA pan-cancer cohorts, MTCYBP28 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTCYBP28 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTCYBP28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCYBP28 expression acts as an unfavorable survival marker, although some lineages such as UCS and ACC show a favorable association.

UVM, THCA, and UCS are the cancer types where MTCYBP28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.133	0.703	.003	93	view →
THCA	OS	Tertile	All	0.918	0.991	<.001	66	view →
UCS	DFS	Tertile	III,IV	0.790	0.176	.015	54	view →
KIRC	DFS	Tertile	III,IV	0.312	0.537	.007	33	view →
TGCT	DFS	Median	II,III,IV	0.711	0.996	.022	24	view →
BRCA	OS	Tertile	IV	0.238	0.703	.012	18	view →
ACC	DFS	Tertile	All	1.000	0.356	.027	15	view →
LUSC	DFS	Tertile	III,IV	0.421	0.864	.018	14	view →
DLBC	OS	Median	All	0.669	1.000	.019	13	view →
STAD	OS	Tertile	II,III,IV	0.593	0.787	.035	6	view →
CESC	DFS	Quartile	All	0.752	0.832	.033	4	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTCYBP28–UVM (DFS)

Open the UVM breakdown →