Across TCGA pan-cancer cohorts, MTCYBP13 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTCYBP13’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MTCYBP13 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCYBP13 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA and KICH are the cancer types where MTCYBP13 tumor–normal differential expression is most reproducible.