MTCO3P9

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MTCO3P9 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MTCO3P9 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher MTCO3P9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO3P9 expression acts as an unfavorable survival marker, although some lineages such as KIRC show a favorable association.

SKCM, UVM, and THYM are the cancer types where MTCO3P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileIV0.0490.502.00245view →
UVMDFSTertileAll0.0320.762<.00145view →
THYMDFSTertileAll0.0750.885<.00127view →
LIHCDFSTertileAll0.1790.568<.00127view →
KIRCDFSTertileIV1.0000.578.01418view →
HNSCDFSTertileIV0.0500.570<.00118view →
LUSCOSTertileIII,IV0.1400.664.01618view →
TGCTDFSTertileII,III,IV0.0880.917.01018view →
ESCADFSTertileAll0.1510.739.00612view →
KICHDFSTertileIV0.2690.784.0459view →
READOSTertileAll0.2820.843.0029view →
LUADOSTertileIII,IV0.2280.677.0159view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MTCO3P9–SKCM (DFS)

Kaplan–Meier survival curve for MTCO3P9 RNA-high vs -low samples in SKCM.

Open the SKCM breakdown →

Exploration