MTCO3P7

Across TCGA pan-cancer cohorts, MTCO3P7 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MTCO3P7 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher MTCO3P7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO3P7 expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

LGG, LUSC, and ESCA are the cancer types where MTCO3P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.409	0.741	.003	36	view →
LUSC	OS	Tertile	All	0.187	0.522	.004	24	view →
ESCA	DFS	Tertile	All	0.379	0.561	.012	18	view →
THCA	OS	Tertile	II,III,IV	0.323	0.914	.013	18	view →
PCPG	DFS	Tertile	All	0.651	0.903	.035	18	view →
BLCA	OS	Tertile	II,III,IV	0.899	0.409	.031	15	view →
STAD	DFS	Tertile	III,IV	0.539	0.301	.035	9	view →
COAD	DFS	Tertile	III,IV	0.170	0.697	.030	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

MTCO3P7–LGG (DFS)

Open the LGG breakdown →