MTCO3P4

Across TCGA pan-cancer cohorts, MTCO3P4 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MTCO3P4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MTCO3P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO3P4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and TGCT show a favorable association.

MESO, SARC, and HNSC are the cancer types where MTCO3P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	126	view →
SARC	OS	Tertile	All	0.377	0.842	<.001	33	view →
HNSC	OS	Tertile	IV	0.570	0.328	.011	24	view →
COAD	OS	Tertile	III,IV	0.163	0.791	.004	18	view →
READ	DFS	Tertile	All	0.090	0.811	<.001	18	view →
TGCT	DFS	Tertile	All	0.929	0.737	.010	14	view →
KIRC	DFS	Tertile	IV	0.340	0.551	.044	12	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MTCO3P4–MESO (OS)

Open the MESO breakdown →