MTCO3P29

Across TCGA pan-cancer cohorts, MTCO3P29 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTCO3P29’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MTCO3P29 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO3P29 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

KIRP, THCA, and UCEC are the cancer types where MTCO3P29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO3P29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	−0.150	.006	6	view →
THCA	Female	II,III,IV	−0.165	.008	3	view →
UCEC	All	IV	+0.475	.013	2	view →
BRCA	All	IV	+0.400	.009	2	view →
LUSC	Female	III,IV	−0.125	.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MTCO3P29–KIRP

Open the KIRP breakdown →