MTCO3P24

Across TCGA pan-cancer cohorts, MTCO3P24 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MTCO3P24 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher MTCO3P24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO3P24 expression acts as an unfavorable survival marker, although some lineages such as PRAD and STAD show a favorable association.

DLBC, HNSC, and TGCT are the cancer types where MTCO3P24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	All	0.062	0.888	<.001	64	view →
HNSC	OS	Tertile	All	0.340	0.616	.011	42	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
PRAD	DFS	Tertile	All	1.000	0.745	.001	18	view →
STAD	DFS	Median	IV	0.468	0.243	.027	16	view →
ACC	OS	Tertile	All	1.000	0.840	.025	12	view →
LIHC	DFS	Tertile	II,III,IV	0.551	0.262	.020	9	view →
BRCA	OS	Tertile	III,IV	0.377	0.585	.043	6	view →
BLCA	OS	Tertile	All	0.682	0.409	.046	6	view →
THCA	OS	Quartile	IV	0.749	0.990	.013	6	view →
OV	OS	Tertile	III,IV	0.264	0.338	.041	4	view →
LGG	OS	Tertile	All	0.962	0.884	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MTCO3P24–DLBC (OS)

Open the DLBC breakdown →